Read More.

Call for Paper - December – 2022 Edition   

(SJIF Impact Factor: 5.966) (IJIFACTOR 3.8, RANKING: A+) (PIF: 3.460)

IJATCA solicits original research papers for the December – 2022 Edition.
Last date of manuscript submission is December 30, 2022.

                                                   

Spectrophotometric Determination of Iron in some Commercial Iron Containing Tablets/Capsule


Volume: 1 Issue: 1
Year of Publication: 2020
Authors: Obruche E. K, Erhabor O. D, Itodo A.U, Itopa S.T



Abstract

A comparative study of the determination of iron composition in some commercial iron tablets/capsule using spectrophotometric method. Spectrophotometric method is based on the formation of complex iron compound- ferrous tris-o-phenanthroline complex by boiling with hydroxylamine hydrochloride and subsequent addition with 1, 10 - phenanthroline at pH ~ 30.2 and the absorbance of this colored solution is measured with a spectrophotometer at 508nm. A calibration curve was found to be linear up to the concentration range of 0.0004 mg/ml to 0.0040 mg/ml. Total four pharmaceutical samples from different pharmaceutical companies were analyzed and results were compared with WHO iron intake for human consumption requirement. The study showed that the total iron content in pharmaceutical samples were 46.41 mg, 28.93 mg, 18.86 mg and 29.54 per 1g of the samples. These values are in good agreement with WHO standard and pharmaceutical range.

References

  1. Beard J.L (2001). Iron biology in immune function, muscles metabolism and neuronal functioning.Nutr.London, 13(2):568-579.

  2. Hallberg and Hulthen V.F, (2000). Effect of iron supplementation on mental and motor development in children. Public health nutrition willians and wilikins,8(5):117-132.

  3. Ionone S, Fairbanks V.F and Brody T. (2004). Significance of an abnormally low or high hemoglobin concentration during pregnancy. Gastroenterology, human press, Pakistan, 30(7):1926-1933.

  4. Lozoff T. (2007). Iron Nutritional Biochemistry in Implication for 02 sensing science. Academic Press, UK, 12(5):464-468.

  5. Stekel S, Fonseca V.A, Alam M.G, and Shah S.V (1983). The role of in diabetes and its complication, Diabetes Care. Desk Reference inc,USA, 30(7):1926-1933.

  6. Thomas D.G, Grant S.L, and Aubuchon-Endsley N.L (2009).The role of iron in neurocognitive development. Food nutr Bull, J Nutr,London, 34(2):196-222.

  7. Wallander M.L, Leiold EA, and Esenstein RS (2006). Molecular control of vertebrate iron homeostasis by iron regulatory proteins. BiochimBiophys Acta, USA, 17(7):668-689.

  8. WHO (2001). Iron Deficiency Anaemia Assessment, Prevention, and Control. A guide for programme manager.

Keywords

Phenanthroline, Spectrophotometric Method, Iron Tablets, Iron Capsule.




© 2022 International Journal of Advanced Trends in Computer Applications
Foundation of Computer Applications (FCA), All right reserved.
Vision & Mission | Privacy Policy | Terms and Conditions